Your health and safety come first. Please read the information below about your medication, possible side effects, and other important safety details. Take this medication only as prescribed by your healthcare provider.
Important Safety Information
Motivated Hard+™ Energy is a compounded prescription product prescribed by medical proviers to treat erectile dysfunction (ED) and support sexual performance. It contains the active ingredients sildenafil, tadalafil, caffeine , Vitamin B3 (niacin), Vitamin B6 (pyridoxal-5-phosphate), and Vitamin B12 (methylcobalamin).
Motivated Hard+™ Energy is a compounded drug. The FDA does not approve or verify compounded drugs for safety, effectiveness, or quality.
STOP! You cannot take this medication if:
- You take medications containing nitrates, use “poppers” (amyl nitrate or butyl nitrate), or take a class of medications called guanylate cyclase stimulators (Riociguat, Adempas).
- You are allergic to sildenafil, tadalafil, caffeine, Vitamin B3, Vitamin B6, Vitamin B12, or any inactive ingredients.
- You are younger than 18 years of age.
- You are a woman.
- You have severe or uncontrolled hypertension.
- You have certain cardiac arrhythmias.
- You have had a cerebrovascular event (e.g., stroke).
STOP taking this medication and seek immediate medical attention if:
- You have an erection that is painful or lasts more than 4 hours.
- You have sudden loss of vision in one or both eyes (possible sign of non-arteritic anterior ischemic optic neuropathy [NAION]).
- You have sudden loss of hearing, ringing in your ears, or dizziness.
- You experience chest pain, shortness of breath, or severe heartburn.
- You develop an allergic reaction. Symptoms may include: swelling of the mouth/lips/tongue or throat, difficulty swallowing, chest pain, shortness of breath, rash, or hives.
- You develop gastrointestinal side effects such as severe nausea, vomiting, diarrhea, or pancreatitis.
- You develop significant sleep disturbance, anxiety, or caffeine withdrawal symptoms.
You NEED to tell your doctor BEFORE taking this medication if:
- You are allergic to this drug or any part of this drug.
- You have pulmonary veno-occlusive disease (PVOD).
- You have retinitis pigmentosa.
- You have sickle cell disease.
- You use "poppers" that contain nitrites.
- You are taking any of these drugs: Cobicistat, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, riociguat, ritonavir, vericiguat, itraconazole, or ketoconazole.
- You are taking another drug that contains sildenafil, tadalafil, caffeine, Vitamin B3, Vitamin B6, or Vitamin B12.
- You are taking another drug for erectile dysfunction.
- You have been told you are not healthy enough for sex or have had a heart attack in the last 90 days, chest pain during sex, heart failure, abnormal heartbeat, blood pressure problems, or a stroke in the last 6 months.
- You are female or a child.
- You have a history of a misshapen penis (Peyronie’s disease).
- You have ever had an erection that was painful or lasted more than 4 hours.
- You have a history of: gastrointestinal ulcers, liver problems, kidney problems or dialysis, bleeding, anemia, blood cancers (e.g., leukemia, cytopenias, myeloma), vision loss or NAION, uncontrolled hypertension, stroke, cardiac arrhythmias, autoimmune disorders, Wilson disease, neurological or mood disorders, or other cancers.
- You have sensitivity to stimulants, sleep disorders, or anxiety disorders (due to caffeine).
Tell your healthcare provider If you are taking any of these drugs:
- Nitrates.
- Guanylate cyclase stimulators (Riociguat, Adempas).
- Alpha-blockers (Hytrin/terazosin, Flomax/tamsulosin, Cardura/doxazosin, Minipress/prazosin, Uroxatral/alfuzosin, Jalyn/dutasteride+tamsulosin, Rapaflo/silodosin).
- Protease inhibitors for HIV (Norvir/ritonavir, Crixivan/indinavir, Fortovase/Invirase/saquinavir, Reyataz/atazanavir).
- Antifungals (Nizoral/ketoconazole, Sporanox/itraconazole).
- Antibiotics (clarithromycin, erythromycin, telithromycin).
- Any medications for blood pressure, erectile dysfunction, or pulmonary artery hypertension (e.g., Revatio).
- Tadalafil is also sold under the brand name Adcirca® for pulmonary arterial hypertension (PAH). Do not take this medication together with Adcirca®, Revatio® (sildenafil), or any other PDE5 inhibitors prescribed for PAH.
- Other stimulants or caffeine-containing medications/supplements.
Other things you should know about this medication
- Talk with your doctor before you drink alcohol while taking this medication.
- This drug does not protect you against sexually transmitted diseases (including HIV).
- This medicine is not a cure for erectile dysfunction and does not increase libido.
- This medication contains caffeine. The recommended daily intake of caffeine for healthy adults is up to 400 mg per day. Consider all dietary sources of caffeine.
- This medication also contains Vitamin B3 and Vitamin B6. The recommended daily limit for Vitamin B3 is 35 mg per day, and for Vitamin B6 is 100 mg per day. Consider all other dietary supplements or multivitamins you may be taking.
- Sexual dysfunction can sometimes be the sign of an underlying health condition such as cardiovascular disease or high cholesterol. Discuss your health with your doctor to ensure that you are healthy enough for sex. If you experience chest pain, dizziness, or nausea during sexual intercourse, seek immediate medical help.
Possible side effects when taking this medication:
- Rash; hives; itching; red, swollen, blistered, or peeling skin, flushing.
- Pressure or pain in the chest, chest tightness, wheezing, trouble breathing.
- Fast or abnormal heartbeat.
- High or low blood pressure.
- Headache, dizziness, imbalance, or fainting.
- Vomiting, reflux, upset stomach, nausea.
- Stroke-like symptoms (weakness, trouble speaking or thinking, facial drooping).
- Change or loss of eyesight or blurriness.
- Swelling of throat/mouth/face/lips/tongue, hoarseness, difficulty swallowing, nasal congestion.
- Ringing in the ears, hearing loss.
- Swelling of extremities.
- Muscle aches or pains, fever.
- Bleeding, bruising.
- Painful erection or erection lasting longer than 4 hours.
- From caffeine: jitteriness, insomnia, anxiety, restlessness, rapid heartbeat, withdrawal if stopped suddenly.
If you experience signs or symptoms of an allergic reaction, stop taking Motivated Hard+™ Energy and seek medical attention immediately.
