Important Safety Information for Motivated Grow+ For Women

Please read this information before starting your medication and again when you receive refills. This guide summarizes important safety information but does not replace instructions from your prescribing clinician or pharmacist.

This product is a compounded oral medication used to support treatment of female pattern hair loss (androgenetic alopecia). Because it is compounded, it is not FDA-approved, and the FDA does not review compounded medications for safety, effectiveness, or manufacturing consistency in the same way it reviews approved drugs.

This medication is intended for women age 18 and older only.

What this medication contains

Each dose contains:
 Minoxidil 1.5 mg
 Biotin 2.5 mg
 L-Cysteine 70 mg
 Zinc 10 mg
 Vitamin B6 4.5 mg
 GHK-Cu 2 mg

What this medication is used for

This medication is prescribed to help treat female pattern hair loss. It combines:

Minoxidil, which is FDA-approved for high blood pressure and is used off-label at low doses to support hair growth
 Biotin, L-Cysteine, Zinc, Vitamin B6, and GHK-Cu, which are included as supportive ingredients in this compounded formulation

Important safety information

Take this medication exactly as prescribed.
 Do not share this medication with anyone else.
Taking more than prescribed will not make it work faster or better.
Hair loss treatment usually requires consistent daily use over several months.
Some patients notice temporary increased shedding early in treatment. This can happen as hair cycles reset and may improve with continued use.

Who should not take this medication

Do not take this medication if any of the following apply to you:

Age under 18 years
 Allergy to minoxidil, biotin, L-cysteine, zinc, vitamin B6, GHK-Cu, or any inactive ingredient in the compounded product
 Pregnant
 Breastfeeding
History of pheochromocytoma
 Significant heart disease, especially if previously advised to avoid vasodilator medications
History of heart failure, unexplained swelling, chest pain syndromes, or other serious cardiovascular disease unless specifically cleared
 Uncontrolled low blood pressure
Current use of another oral minoxidil product
Use of medications that may interact and increase risk, depending on your full medication list

Before starting this medication, tell your prescriber if you have or have ever had:

Low blood pressure, dizziness, or fainting
Palpitations, rapid heartbeat, arrhythmia, or other heart problems
Swelling in the legs, ankles, or around the eyes
Shortness of breath
Kidney disease
Liver disease
Any history of pericardial disease
Any medication allergies
Any supplements or vitamins you take regularly

Medication and supplement precautions

Tell your prescriber and pharmacist about all prescription medicines, over-the-counter medicines, vitamins, and supplements you take.

Important precautions include:

Do not use with other oral minoxidil products
Use caution with other vitamins or supplements so you do not unintentionally take excessive amounts of overlapping ingredients
This product already contains biotin 2.5 mg. Avoid adding extra high-dose biotin unless specifically instructed
High-dose biotin can interfere with certain lab tests, including some tests used in emergency heart evaluation
This product contains zinc 10 mg. Check other supplements to avoid unnecessary excess zinc intake

How to take it

Take by mouth exactly as prescribed, usually once daily
It may be taken with or without food
If it causes lightheadedness, taking it later in the day may be helpful if that matches the prescription instructions
If you miss a dose, skip the missed dose and take the next dose as scheduled
 Do not double up doses

What to expect

Hair shedding can increase temporarily in the first several weeks
Visible improvement may take several months
Full benefit often requires ongoing use
If you stop treatment, hair loss will usually gradually return toward its prior pattern over time

Common side effects

Possible side effects may include:

Increased hair growth on the face or body
Lightheadedness or dizziness
Fast heartbeat or palpitations
Headache
Leg swelling or fluid retention
Swelling around the eyes
Nausea
Trouble sleeping
Mild stomach upset

Less common but important possible side effects

Worsening swelling
Persistent rapid or irregular heartbeat
Shortness of breath
Significant weight gain from fluid retention
Severe allergic reaction such as rash, hives, or swelling

Serious symptoms: stop the medication and seek urgent medical care right away

Stop taking this medication and get urgent medical attention if you develop:

Chest pain
 Shortness of breath
 Fainting
 Severe dizziness
 Rapid, pounding, or irregular heartbeat that does not improve
 New or worsening swelling of the legs, feet, face, or around the eyes
 Sudden severe symptoms such as weakness, trouble speaking, or facial droop
 Severe allergic reaction such as swelling of the lips, tongue, or throat; wheezing; or trouble breathing

Use with caution in patients with cardiovascular risk

Because this product contains oral minoxidil, monitor for:

Dizziness or blood pressure-related symptoms
Fast heart rate
Swelling or fluid retention
Chest symptoms
Breathing changes

Patients with cardiovascular, kidney, or liver disease may need additional evaluation before use.

Laboratory and test considerations

Tell healthcare staff before testing that you are taking this medication because:

Biotin may interfere with certain blood tests
 Minoxidil may affect heart rate or blood pressure readings

Storage

Store at room temperature
Keep in the original container from the pharmacy
Keep out of reach of children and pets

Pet safety

Minoxidil can be harmful to pets. Keep this medication away from dogs, cats, and other animals.

Disposal

If the medication is expired or no longer needed, use a medication take-back program if available. If no take-back option is available, follow pharmacist or local disposal guidance.

General reminders

This medication is prescribed only for the person named on the prescription
Do not use it for another condition
Do not give it to anyone else
If your health history, medications, or supplements change, notify the prescribing team because the safety of this medication may also change

Supporting References:

1. Low-dose oral minoxidil initiation for patients with hair loss: an international modified delphi consensus statement. JAMA Dermatology, 2025
2. minoxidil PO. FDA, 2025
3. Safety of low-dose oral minoxidil for hair loss: a multicenter study of 1404 patients. Journal of the American Academy of Dermatology, 2021
4. Low-dose oral minoxidil does not significantly affect blood pressure: a systematic review and meta-analysis. Journal of the American Academy of Dermatology, 2025
5. Serious complication of low-dose oral minoxidil for hair loss. JAAD Case Reports, 2022
6. Addressing the root causes of female hair loss and non-pharmaceutical interventions. Journal of Drugs in Dermatology, 2025
7. Female pattern hair loss and androgen excess: a report from the multidisciplinary androgen excess and PCOS committee. The Journal of Clinical Endocrinology and Metabolism, 2019